%0 Journal Article
%T Surgical treatment of synchronous multiple lung adenocarcinomas: experiment of 171 cases
%A Ikeda, Koei
%A Fujino, Kosuke
%A Masuda, Yoshiko
%A Suzuki, Makoto
%J Journal of Visualized Surgery
%D 2020
%B 2020
%9 
%! Surgical treatment of synchronous multiple lung adenocarcinomas: experiment of 171 cases
%K 
%X Background: It is unclear how to treat synchronous multiple lung adenocarcinoma (SMLA) cases, which are increasing with the development of high-resolution computed tomography (HRCT).  Methods: Retrospective review of 171 cases of SMLA who underwent curative intent surgery between 2010 and 2018. Lung volume-preserving surgery, segmentectomy or wedge resection, is preferred for ground glass opacity nodules (GGN) within 2.0 cm. Clinical observation is allowed for pure GGN within 1.0 cm.   Results: The 5-year recurrence-free survival rate after surgery was 95.2%, and the overall survival rate was 93%. Prognosis was correlated with the degree of progression of the dominant tumor. Tumor number, surgical procedure and remnant tumor after surgery were not correlated with prognosis.  Conclusions: The prognosis of SMLA was relatively good, and was dependent on the stage and malignant potential of the dominant tumor. Limited resection and clinical observation for GGN are acceptable.
%U https://jovs.amegroups.org/article/view/34337
%V 6
%P 
%@ 2221-2965